Healing the Broken Brain Syndrome

In an exclusive interview with Life Extension magazine, Dr. Hyman, who is the founder and medical director of the UltraWellness Center in Lenox, Massachusetts, talks about his remarkable findings. He explains how problems of the brain, such as depression, anxiety, bipolar disease, attention deficit disorder (ADD), Alzheimer’s disease, Parkinson’s disease, and mood swings can be prevented, improved, or even cured by his innovative program of diet, nutritional supplements, exercise, meditation, and lifestyle changes. Dr. Hyman’s findings are a harbinger of a new approach to dealing with what he calls “broken brains,” representing a more natural, healthy, and effective method that might one day make traditional psychiatric medication and treatment obsolete.

Why Functional Medicine?

Referring to the widespread incidence and exorbitant cost of treating mental disorders, Dr. Hyman explains that, “Functional medicine is a map or model for addressing a chronic disease epidemic which affects over half of Americans and costs 80% of our health care dollars.” He says that while conventional methods are effective for acute illness, they simply do not do the job with chronic disease.

“We need to change access to health care and create improved coverage for our population,” he adds, “But we have to change the type of health care we have access to.”

Dr. Hyman says that functional medicine grows out of Western science and predicts, “It will reinvigorate primary care medicine and provide success, where today there is mostly failure, in addressing the epidemic of chronic conditions like heart disease, diabetes, obesity, autoimmune disease, digestive problems, and brain and mood disorders.”
He does not reject scientific medicine and, in fact, the future of scientific medicine is functional medicine. Dr. Hyman also distinguishes functional medicine from alternative or integrative medicine.

The key difference lies in functional medicine’s focus on finding the root causes of an individual’s health problems, as opposed to a focus on prescribing alternative treatments such as acupuncture or biofeedback for conventional symptom-based diagnoses.

The aim, he says, “Is to navigate through the maze of chronic disease and understand the very few basic things that can go wrong, that can cause a myriad of symptoms and be easily corrected by addressing the root. So if you have depression because you have a vitamin B12 deficiency, or you have a food allergy or you have mercury poisoning or your thyroid is not functioning properly or you’ve had some psychological trauma, each one of these things is different and needs a different treatment.”

The Epidemic of Emotional Disorders and Their Causes

“We have 1.1 billion people in the world with mood problems or cognitive disorders,” explains Dr. Hyman. “One in 10 Americans is on antidepressants, one in 10 children are on stimulant medication, and one in four people will be affected by major depression during their lifetime. Today, we have a chance to fundamentally address the causes. This has never really been possible before, because we never understood how biology works and how it all fits together.”
As he explains in The UltraMind Solution,

“There are only a few, common underlying mechanisms responsible for all disease. Our diet is becoming increasingly toxic, our environment is increasingly toxic, we have significant nutritional imbalances and deficiencies, and we’re under constant stress.

The results weigh on us day after day after day.” He adds that while we cannot escape exposure to all environmental toxins, we can avoid many in food, water, and pesticides.
“The average person consumes a gallon of neurotoxic pesticides a year,” Dr. Hyman remarks, “And there are 3,500 different additives put into our food supply.”

In his new book, he explains that the old idea that the blood-brain barrier acts as an impenetrable shield against harmful elements is no longer sufficient. “What I found,” he says, “Much to my surprise, was that when I treated people for problems with insulin, or when I treated food allergies or when I got people detoxed from heavy metals, their mental problems also went away. Their mood got better, their depression lifted, their dementia reversed. There were children with autism who began to talk again and others I treated for asthma or allergies who suddenly found their attention deficit disorder (ADD) went away. They went from having brain chaos to having healthy inner brain function. And I said, ‘Wow, what’s going on here?’”

Does Everyone Need Supplements?

Dr. Hyman writes that if people “eat wild, fresh, organic, local, non-genetically modified food grown in virgin mineral- and nutrient-rich soils that has not been transported across vast distances and stored for months before being eaten... and work and live outside, breathe only fresh unpolluted air, drink only pure, clean water, sleep nine hours a night, move their bodies every day, and are free from chronic stressors and exposure to environmental toxins,” then, perhaps, they might not need supplements.

For the rest of us, whom he considers to be all of us, supplements are an absolute necessity. His book lists daily nutrients that he considers basic for everyone, including vitamins A, B1, B2, B3, B6, B12, C, D, E, K, carotenoids, biotin, choline, and inositol; macrominerals calcium, chloride, magnesium, phosphorus, potassium, sodium, and sulfur; trace minerals copper, iodine, iron, manganese, molybdenum, selenium, vanadium, zinc, boron, chromium, and silicon; essential amino acids tryptophan, meth-ionine, phenylalanine, threonine, valine, leucine, isoleucine, and lysine; and essential fatty acids linoleic acid, gamma-linolenic acid (GLA), alpha-linoleic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
“Think of nutrients as fertilizer for your brain,” Dr. Hyman says. “Think of them as little helpers that improve communications and connections.” He believes that approximately 80% of us will do well and maintain a healthy brain on basic supplements (combined with a healthy lifestyle and diet), including a high-quality multivitamin; calcium and magnesium; vitamin D3, omega-3 fatty acids; probiotics; and the methylation factors folic acid, B6, and B12.

Better Diet, Better Brain

Dr. Hyman has a simple two-fold approach for improving both brain and body: take out the bad stuff and put in the good stuff. He pinpoints a few dietary elements as causes of major mental and physical problems, urging us to eliminate them from our menu: gluten and dairy, which he calls “staples of our American diet;” sugar and high-fructose corn syrup; trans or hydrogenated fats, which he calls “markers of poor quality food;” and artificial sweeteners.


“Hidden food allergies are a major unrecognized epidemic in the twenty-first century,” he asserts, adding that most of us fail to make the connection between what we eat and what we feel.
“Optimal nutrition is the most important factor in keeping your brain healthy,” says Dr. Hyman. “Feeding your brain is not something most of us know how to do.” He explains that most doctors know little or nothing about proper nutrition, something that is slowly beginning to change, as it becomes more evident that “vitamins and minerals are so essential for brain function and health.”
Pinpointing carbohydrates as “the single most important food for long-term health and brain function,” Dr. Hyman advises eating “real, whole food as it comes from the earth,” including fresh vegetables, fruit, beans, whole grains, nuts, seeds, herbs, and spices, and lean animal protein such as fish, chicken, and eggs.
Ideally, should we eat only organic food? “It’s preferable,” he responds, “But not necessary. If it’s a choice of eating organic or getting off gluten and dairy, get off the gluten and dairy.” He also advises eating food that is as low as possible in pesticides, and recommends checking the website of the Environmental Working Group (http://www.lef.org/www.ewg.org), which lists the latest figures on amounts of pesticides in foods.

Important Lifestyle Factors

As part of his program, Dr. Hyman emphasizes the need to confront the harm that daily stress does to our minds and bodies (which includes increasing levels of cortisol), and to be proactive in diminishing this contributor to “broken brains.” He mentions the importance of a good night’s sleep, noting findings that Americans are sleep-deprived, which can have a powerful effect on brain function. As an example, he points to indicated links between sleep deprivation and Alzheimer’s disease.

'He also recommends regular meditation, which improves mood and cognitive function, yoga, deep breathing, laughter therapy, biofeedback, making love, hypnosis, and exercise, and advises everyone to do at least one every day'.

Staying Young

Balancing hormones is also a part of Dr. Hyman’s program. He notes that in the US, there are three big epidemics of hormonal imbalance: too much insulin (from sugar intake); too much cortisol and adrenaline (from stress); and not enough thyroid hormone. He says that all three interconnect and affect our sex hormones.
“I believe that most of the symptoms of aging we see are really symptoms of abnormal aging or dysfunction that are related to imbalances in our core body systems,” he concludes. Dr. Hyman recommends bioidentical hormones, which he says can be “life-saving” when used correctly.

How the Doctor Stays Well

As a physician who is strongly motivated to solve medical puzzles, Dr. Hyman has paid close attention to his own health since his bout with mercury poisoning. “I have the unique benefit of knowing my particular genetic potholes,” he says, “And I also know I had chronic fatigue and work very hard, so I take a number of supplements to help me deal with that.”
Dr. Hyman’s personal supplement program includes the following:

-Multivitamin
-Fish oil
-Vitamin D3
-Magnesium
-Coenzyme Q10
-Acetyl-L-carnitine
-Methylating nutrients (such as vitamins B6, B12, and folic acid).

Dr. Hyman’s overall wellness plan? “I keep my gut healthy, keep myself free of toxins, and keep my mitochondria healthy. I exercise at least four or five times a week, get enough sleep, eat whole, real food, keep my sugar intake at a minimum, enjoy alcohol as a treat once in a while, and make sure I hit the pause button every day or two.”

A Life With Goals

In his book-The UltraMind Solution, Dr. Hyman writes, “My goal for all of you is to live your life as you were meant to live it—a life full of energy, vitality, pleasure, and happiness.” Noting that, “The brain is not disconnected from the rest of the body as many practitioners of conventional medicine would have you believe,” he hopes to change the way we treat mental problems and help us realize that the causes often lie in places where we haven’t been looking: our diet, nutrient deficiencies, and toxins that have invaded our bodies.

Adapted from article in Life Extension Magazine, March 2009

http://www.lef.org/magazine/mag2009/mar2009_Mark-Hyman-Healing-Broken-Brain-Syndrome_01.htm