"And He feeds me and quenches my thirst and when I fall sick then He (Allah) cures me" [Soorah Shu'araa: 80]


11.7.08

The Dangers of Chronic Inflammation


Just now I had a patient who asked me about the danger of 'keradangan darah' (chronic inflammation). apparently he got his blood tested somewhere and told that his 'inflammatory marker' (I presumed it is c-reactive protein) was somewhat high and it's not so good.

First of all, what is inflammation?

Imagine you had a fall and injured your ankle-then you got the pain, swelling, redness etc. that means your white blood cells go attacking the injured place and release a few inflammatory substances to help you heal from the injury. well, the process of inflammation is very much needed in our everyday's life, the problem arises when it is not under controlled and that will causes a lot of problems
The article below is simplified from Life Extension about chronic inflammation.you can read the full article here

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Chronic inflammation is involved in diseases as diverse as atherosclerosis, cancer, heart valve dysfunction, obesity, diabetes, congestive heart failure, digestive system diseases, and Alzheimer's disease.

In aged people with multiple degenerative diseases, the inflammatory marker, C-reactive protein, is often sharply elevated, indicating the presence of an underlying inflammatory disorder.CRP also can predict your risk of getting heart attack. Studies showed that people with high levels of C-reactive protein were almost three times as likely to die from a heart attack

What Causes Elevated C-reactive Protein?

  • Cooking foods at high temperatures results in a "browning" effect, where sugars and certain oxidized fats react with proteins to form glycotoxins in the food.this leads to chronic inflammatory process

  • Consuming low glycemic foods prevents the insulin surge that contributes to chronic inflammatory processes. It is also important to avoid over consumption of foods high in arachidonic acid (beef, egg yolk, dairy, etc.).

Reducing Inflammation

The following supplements are suggested:





  • The docosahexaenoic acid (DHA) fraction of fish oil may be the most effective nonprescription supplement to suppress pro-inflammatory cytokines. Gamma-linolenic acid (GLA) is a precursor of PGE1, a potent anti-inflammatory agent

  • DHEA is a hormone that decreases with age. DHEA has been shown to suppress IL-6, an inflammatory cytokine that often increases as people age. Typical doses of DHEA are 25-50 mg daily, although some people take 100 mg daily.

  • Nettle leaf has been shown to suppress the proinflammatory cytokine TNF-a. Take 1000 mg daily.

  • Vitamin E and N-acetyl-cysteine (NAC) are protective antioxidants with anti-inflammatory properties. Vitamin E that contains gamma-tocopherol and tocotrienols provides the most broad-spectrum protection

  • Vitamin K helps reduce levels of IL-6, a pro-inflammatory messenger

  • Consuming at least 1000 mg per day of carnosine

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